Synergistic Toll-like Receptor 3/9 Signaling Affects Properties and Impairs Glioma-Promoting Activity of Microglia

In murine experimental glioma models, TLR3 or TLR9 activation of microglial/macrophages has been shown to impair glioma growth, which could, however, not been verified in recent clinical trials. We therefore tested whether combined TLR3 and TLR9 activation of microglia/macrophages would have a syner...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Huang, Yimin, Zhang, Quan, Lubas, Malgorzata, Yuan, Yang, Yalcin, Fatih, Efe, Ibrahim E., Xia, Pengfei, Motta, Edyta, Buonfiglioli, Alice, Lehnardt, Seija, Dzaye, Omar, Flueh, Charlotte, Synowitz, Michael, Hu, Feng, Kettenmann, Helmut
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2020
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424875/
https://ncbi.nlm.nih.gov/pubmed/32631940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0666-20.2020
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