Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion

BACKGROUND: Glioblastomas are the most aggressive primary brain tumors in humans. Microglia/brain macrophage accumulation in and around the tumor correlates with malignancy and poor clinical prognosis of these tumors. We have previously shown that microglia promote glioma expansion through upregulat...

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Detalhes bibliográficos
Main Authors: Vinnakota, Katyayni, Hu, Feng, Ku, Min-Chi, Georgieva, Petya B., Szulzewsky, Frank, Pohlmann, Andreas, Waiczies, Sonia, Waiczies, Helmar, Niendorf, Thoralf, Lehnardt, Seija, Hanisch, Uwe-Karsten, Synowitz, Michael, Markovic, Darko, Wolf, Susanne A., Glass, Rainer, Kettenmann, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813418/
https://ncbi.nlm.nih.gov/pubmed/24014382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not115
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