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Advances in Bacterial Methionine Aminopeptidase Inhibition

Methionine aminopeptidases (MetAPs) are metalloenzymes that cleave the N-terminal methionine from newly synthesized peptides and proteins. These MetAP enzymes are present in bacteria, and knockout experiments have shown that MetAP activity is essential for cell life, suggesting that MetAPs are good...

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Detalhes bibliográficos
Publicado no:Curr Top Med Chem
Main Authors: Helgren, Travis R., Wangtrakuldee, Phumvadee, Staker, Bart L., Hagen, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009474/
https://ncbi.nlm.nih.gov/pubmed/26268344
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