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The Identification of Inhibitory Compounds of Rickettsia prowazekii Methionine Aminopeptidase for Antibacterial Applications
Methionine aminopeptidase (MetAP) is a dinuclear metallo-protease responsible for the cleavage of methionine initiator residues from nascent proteins. MetAP activity is necessary for bacterial proliferation and is therefore a projected novel antibacterial target. A compound library consisting of 294...
में बचाया:
| में प्रकाशित: | Bioorg Med Chem Lett |
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| मुख्य लेखकों: | , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5908248/ https://ncbi.nlm.nih.gov/pubmed/29551481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.03.002 |
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