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Discovery of Inhibitors of Burkholderia pseudomallei Methionine Aminopeptidase with Antibacterial Activity
[Image: see text] Evaluation of a series of MetAP inhibitors in an in vitro enzyme activity assay led to the first identification of potent molecules that show significant growth inhibition against Burkholderia pseudomallei. Nitroxoline analogues show excellent inhibition potency in the BpMetAP1 enz...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
American Chemical Society
2013
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ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871185/ https://ncbi.nlm.nih.gov/pubmed/24376907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400034m |
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