Discovery of Inhibitors of Burkholderia pseudomallei Methionine Aminopeptidase with Antibacterial Activity

[Image: see text] Evaluation of a series of MetAP inhibitors in an in vitro enzyme activity assay led to the first identification of potent molecules that show significant growth inhibition against Burkholderia pseudomallei. Nitroxoline analogues show excellent inhibition potency in the BpMetAP1 enz...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wangtrakuldee, Phumvadee, Byrd, Matthew S., Campos, Cristine G., Henderson, Michael W., Zhang, Zheng, Clare, Michael, Masoudi, Ali, Myler, Peter J., Horn, James R., Cotter, Peggy A., Hagen, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871185/
https://ncbi.nlm.nih.gov/pubmed/24376907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400034m
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados