Live Attenuated Leishmania donovani Centrin Knock Out Parasites Generate Non-inferior Protective Immune Response in Aged Mice against Visceral Leishmaniasis

BACKGROUND: Visceral leishmaniasis (VL) caused by the protozoan parasite Leishmania donovani causes severe disease. Age appears to be critical in determining the clinical outcome of VL and at present there is no effective vaccine available against VL for any age group. Previously, we showed that gen...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS Negl Trop Dis
Main Authors: Bhattacharya, Parna, Dey, Ranadhir, Dagur, Pradeep K., Joshi, Amritanshu B., Ismail, Nevien, Gannavaram, Sreenivas, Debrabant, Alain, Akue, Adovi D., KuKuruga, Mark A., Selvapandiyan, Angamuthu, McCoy, John Philip, Nakhasi, Hira L.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2016
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007048/
https://ncbi.nlm.nih.gov/pubmed/27580076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004963
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