Live Attenuated Leishmania donovani Centrin Knock Out Parasites Generate Non-inferior Protective Immune Response in Aged Mice against Visceral Leishmaniasis

BACKGROUND: Visceral leishmaniasis (VL) caused by the protozoan parasite Leishmania donovani causes severe disease. Age appears to be critical in determining the clinical outcome of VL and at present there is no effective vaccine available against VL for any age group. Previously, we showed that gen...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Negl Trop Dis
Päätekijät: Bhattacharya, Parna, Dey, Ranadhir, Dagur, Pradeep K., Joshi, Amritanshu B., Ismail, Nevien, Gannavaram, Sreenivas, Debrabant, Alain, Akue, Adovi D., KuKuruga, Mark A., Selvapandiyan, Angamuthu, McCoy, John Philip, Nakhasi, Hira L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007048/
https://ncbi.nlm.nih.gov/pubmed/27580076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004963
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