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Immunization with Live Attenuated Leishmania donovani Centrin(−/−) Parasites Is Efficacious in Asymptomatic Infection

Currently, there is no vaccine against visceral leishmaniasis (VL). Toward developing an effective vaccine, we have reported extensively on the immunogenicity of live attenuated LdCentrin(−/−) mutants in naive animal models. In VL endemic areas, asymptomatic carriers outnumber symptomatic cases of V...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ismail, Nevien, Kaul, Amit, Bhattacharya, Parna, Gannavaram, Sreenivas, Nakhasi, Hira L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732910/
https://ncbi.nlm.nih.gov/pubmed/29312315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01788
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