Immunization with Live Attenuated Leishmania donovani Centrin(−/−) Parasites Is Efficacious in Asymptomatic Infection

Currently, there is no vaccine against visceral leishmaniasis (VL). Toward developing an effective vaccine, we have reported extensively on the immunogenicity of live attenuated LdCentrin(−/−) mutants in naive animal models. In VL endemic areas, asymptomatic carriers outnumber symptomatic cases of V...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Ismail, Nevien, Kaul, Amit, Bhattacharya, Parna, Gannavaram, Sreenivas, Nakhasi, Hira L.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732910/
https://ncbi.nlm.nih.gov/pubmed/29312315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01788
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