Lataa...
Stimulating the RIG-I pathway to kill cells in the latent HIV reservoir following viral reactivation
The persistence of latent HIV proviruses in long-lived CD4(+) T cells despite antiretroviral therapy (ART)(1–3) is a major obstacle to viral eradication(4–6). Because current candidate latency-reversing agents (LRAs) induce HIV transcription but fail to clear these cellular reservoirs,(7–8) new appr...
Tallennettuna:
| Julkaisussa: | Nat Med |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2016
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5004598/ https://ncbi.nlm.nih.gov/pubmed/27294875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4124 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|