Stimulation of HIV-1-specific cytolytic T-lymphocytes facilitates elimination of latent viral reservoir after virus reactivation

Highly active antiretroviral therapy (HAART) suppresses HIV-1 replication but cannot eliminate the virus because HIV-1 establishes latent infection. Interruption of HAART leads to a rapid rebound of viremia. Life-long treatment is therefore required. Efforts to purge the latent reservoir have focuse...

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Bibliographische Detailangaben
Hauptverfasser: Shan, Liang, Deng, Kai, Shroff, Neeta S., Durand, Christine, Rabi, S. Alireza., Yang, Hung-Chih, Zhang, Hao, Margolick, Joseph B., Blankson, Joel N., Siliciano, Robert F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501645/
https://ncbi.nlm.nih.gov/pubmed/22406268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.01.014
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