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Rapid Quantification of the Latent Reservoir for HIV-1 Using a Viral Outgrowth Assay
HIV-1 persists in infected individuals in a stable pool of resting CD4(+) T cells as a latent but replication-competent provirus. This latent reservoir is the major barrier to the eradication of HIV-1. Clinical trials are currently underway investigating the effects of latency-disrupting compounds o...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3667757/ https://ncbi.nlm.nih.gov/pubmed/23737751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003398 |
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