Rapid Quantification of the Latent Reservoir for HIV-1 Using a Viral Outgrowth Assay

HIV-1 persists in infected individuals in a stable pool of resting CD4(+) T cells as a latent but replication-competent provirus. This latent reservoir is the major barrier to the eradication of HIV-1. Clinical trials are currently underway investigating the effects of latency-disrupting compounds o...

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Bibliografiska uppgifter
Huvudupphovsmän: Laird, Gregory M., Eisele, Evelyn E., Rabi, S. Alireza, Lai, Jun, Chioma, Stanley, Blankson, Joel N., Siliciano, Janet D., Siliciano, Robert F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667757/
https://ncbi.nlm.nih.gov/pubmed/23737751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003398
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