Quantitation of the latent HIV-1 reservoir from the sequence diversity in viral outgrowth assays

BACKGROUND: The ability of HIV-1 to integrate into the genomes of quiescent host immune cells, establishing a long-lived latent viral reservoir (LVR), is the primary obstacle to curing these infections. Quantitative viral outgrowth assays (QVOAs) are the gold standard for estimating the size of the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Retrovirology
Egile Nagusiak: Poon, Art F. Y., Prodger, Jessica L., Lynch, Briana A., Lai, Jun, Reynolds, Steven J., Kasule, Jingo, Capoferri, Adam A., Lamers, Susanna L., Rodriguez, Christopher W., Bruno, Daniel, Porcella, Stephen F., Martens, Craig, Quinn, Thomas C., Redd, Andrew D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2018
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034329/
https://ncbi.nlm.nih.gov/pubmed/29976219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-018-0426-1
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