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From reactivation of latent HIV-1 to elimination of the latent reservoir: the presence of multiple barriers to viral eradication

The discovery of a stable latent reservoir for HIV-1 in resting memory CD4(+) T cells provides a mechanism for lifelong persistence of HIV-1. The long-lived latently infected cells persist in spite of prolonged highly active antiretroviral therapy and present a major barrier to a cure of HIV-1 infec...

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Detalhes bibliográficos
Publicado no:Bioessays
Main Authors: Shan, Liang, Siliciano, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386637/
https://ncbi.nlm.nih.gov/pubmed/23613347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201200170
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