Chronic exposure to IFNα drives medullar lymphopoiesis towards T-cell differentiation in mice

Interferon-α is a potent antiviral agent and a vigorous adjuvant in the induction of T-cell responses but its use is limited by hematologic toxicity. Interferon-α alters hematopoietic stem cell dormancy and impairs myelocytic and erythrocytic/megakaryocytic differentiation from hematopoietic progeni...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Di Scala, Marianna, Gil-Fariña, Irene, Vanrell, Lucia, Sánchez-Bayona, Rodrigo, Alignani, Diego, Olagüe, Cristina, Vales, Africa, Berraondo, Pedro, Prieto, Jesús, González-Aseguinolaza, Gloria
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004416/
https://ncbi.nlm.nih.gov/pubmed/25715405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.115410
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