Development of a Liver-specific Tet-On Inducible System for AAV Vectors and Its Application in the Treatment of Liver Cancer

Recombinant adeno-associated virus (rAAV) are effective gene delivery vehicles that can mediate long-lasting transgene expression. However, tight regulation and tissue-specific transgene expression is required for certain therapeutic applications. For regulatable expression from the liver we designe...

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Detalhes bibliográficos
Main Authors: Vanrell, Lucia, Di Scala, Marianna, Blanco, Laura, Otano, Itziar, Gil-Farina, Irene, Baldim, Victor, Paneda, Astrid, Berraondo, Pedro, Beattie, Stuart G, Chtarto, Abdelwahed, Tenenbaum, Lilianne, Prieto, Jesús, Gonzalez-Aseguinolaza, Gloria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129565/
https://ncbi.nlm.nih.gov/pubmed/21364542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.37
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