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Liver-directed gene therapy of chronic hepadnavirus infection using interferon alpha tethered to apolipoprotein A-I

BACKGROUND & AIMS: Current HBV management is challenging as treatment with nucleos(t)ide analogs needs to be maintained indefinitely and because IFNα therapy is associated with considerable toxicity. Previously we showed that linking IFNα to apolipoprotein A-I generates a molecule (IA) with dist...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Hepatol
Main Authors: Berraondo, Pedro, Di Scala, Marianna, Korolowicz, Kyle, Thampi, Linta M., Otano, Itziar, Suarez, Lester, Fioravanti, Jessica, Aranda, Fernando, Ardaiz, Nuria, Yang, Junming, Kallakury, Bhaskar V., Tucker, Robin D., Vasquez, Marcos, Menne, Stephan, Prieto, Jesús, González-Aseguinolaza, Gloria
פורמט: Artigo
שפה:Inglês
יצא לאור: 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508219/
https://ncbi.nlm.nih.gov/pubmed/25772035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.02.048
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