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Antitumor effect of an adeno-associated virus expressing apolipoprotein A-1 fused to interferon alpha in an interferon alpha-resistant murine tumor model

Interferon alpha (IFNα) is a cytokine approved for the treatment of several types of cancer. However, the modest effect on overall survival and the high toxicity associated with the treatment has reduced the clinical use of this cytokine. In this study, we have developed a tumor model that reproduce...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Vasquez, Marcos, Paredes-Cervantes, Vladimir, Aranda, Fernando, Ardaiz, Nuria, Gomar, Celia, Berraondo, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354905/
https://ncbi.nlm.nih.gov/pubmed/28029653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14127
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