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Antitumor effect of an adeno-associated virus expressing apolipoprotein A-1 fused to interferon alpha in an interferon alpha-resistant murine tumor model

Interferon alpha (IFNα) is a cytokine approved for the treatment of several types of cancer. However, the modest effect on overall survival and the high toxicity associated with the treatment has reduced the clinical use of this cytokine. In this study, we have developed a tumor model that reproduce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Vasquez, Marcos, Paredes-Cervantes, Vladimir, Aranda, Fernando, Ardaiz, Nuria, Gomar, Celia, Berraondo, Pedro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354905/
https://ncbi.nlm.nih.gov/pubmed/28029653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14127
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