Treatment with the Immunomodulator AIC649 in Combination with Entecavir Produces Antiviral Efficacy in the Woodchuck Model of Chronic Hepatitis B

As current interventions for chronic hepatitis B (CHB) rarely induce cure, more effective drugs are needed. Short-term treatment of woodchucks with the novel immunomodulator AIC649, a parapoxvirus-based stimulator of toll-like receptor 9 dependent and independent pathways, has been shown to reduce v...

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Publicado no:Viruses
Main Authors: Korolowicz, Kyle E., Suresh, Manasa, Li, Bin, Huang, Xu, Yon, Changsuek, Leng, Xuebing, Kallakury, Bhaskar V., Tucker, Robin D., Menne, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069054/
https://ncbi.nlm.nih.gov/pubmed/33918831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13040648
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