Treatment of Chronic Viral Hepatitis in Woodchucks by Prolonged Intrahepatic Expression of Interleukin-12

Chronic hepatitis B is a major cause of liver-related death worldwide. Interleukin-12 (IL-12) induction accompanies viral clearance in chronic hepatitis B virus infection. Here, we tested the therapeutic potential of IL-12 gene therapy in woodchucks chronically infected with woodchuck hepatitis viru...

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Autores principales: Crettaz, Julien, Otano, Itziar, Ochoa, Laura, Benito, Alberto, Paneda, Astrid, Aurrekoetxea, Igor, Berraondo, Pedro, Rodríguez-Madoz, Juan Roberto, Astudillo, Aurora, Kreppel, Florian, Kochanek, Stefan, Ruiz, Juan, Menne, Stephan, Prieto, Jesus, Gonzalez-Aseguinolaza, Gloria
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648282/
https://ncbi.nlm.nih.gov/pubmed/19116251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02384-08
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