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Isoform-specific targeting of ROCK proteins in immune cells
Rho-associated kinase 1 (ROCK1) and ROCK2 are activated by Rho GTPase and control cytoskeleton rearrangement through modulating the phosphorylation of their down-stream effector molecules. Although these 2 isoforms share more than 90% homology within their kinase domain the question of whether ROCK...
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Publicado no: | Small GTPases |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5003547/ https://ncbi.nlm.nih.gov/pubmed/27254302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1181698 |
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