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Optical tools to study the isoform-specific roles of small GTPases in immune cells
Despite the 92% homology of the hematopoietic cell-specific Rac2 to the canonical isoform Rac1, these isoforms have been shown to play non-redundant roles in immune cells. To study isoform-specific dynamics of Rac in live cells we developed a genetically-encoded, single-chain FRET-based biosensor fo...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4821714/ https://ncbi.nlm.nih.gov/pubmed/26951800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501655 |
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