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ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings
Rho-associated kinase 2 (ROCK2) determines the balance between human T helper 17 (T(H)17) cells and regulatory T (T(reg)) cells. We investigated its role in the generation of T follicular helper (T(FH)) cellswhich provide help necessary to generate antibody-producing B cells in normal and autoimmune...
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| I publikationen: | Sci Signal |
|---|---|
| Huvudupphovsmän: | , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5193229/ https://ncbi.nlm.nih.gov/pubmed/27436361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aad8953 |
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