HIV-1 integrase binds the viral RNA genome and is essential during virion morphogenesis

While an essential role of HIV-1 integrase (IN) for integration of viral cDNA into human chromosome is established, studies with IN mutants and allosteric IN inhibitors (ALLINIs) have suggested that IN can also influence viral particle maturation. However, it has remained enigmatic as to how IN cont...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Kessl, Jacques J., Kutluay, Sebla B., Townsend, Dana, Rebensburg, Stephanie, Slaughter, Alison, Larue, Ross C., Shkriabai, Nikoloz, Bakouche, Nordine, Fuchs, James R., Bieniasz, Paul D., Kvaratskhelia, Mamuka
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003418/
https://ncbi.nlm.nih.gov/pubmed/27565348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.07.044
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