HIV-1 integrase binds the viral RNA genome and is essential during virion morphogenesis

While an essential role of HIV-1 integrase (IN) for integration of viral cDNA into human chromosome is established, studies with IN mutants and allosteric IN inhibitors (ALLINIs) have suggested that IN can also influence viral particle maturation. However, it has remained enigmatic as to how IN cont...

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Publicado en:Cell
Autores principales: Kessl, Jacques J., Kutluay, Sebla B., Townsend, Dana, Rebensburg, Stephanie, Slaughter, Alison, Larue, Ross C., Shkriabai, Nikoloz, Bakouche, Nordine, Fuchs, James R., Bieniasz, Paul D., Kvaratskhelia, Mamuka
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003418/
https://ncbi.nlm.nih.gov/pubmed/27565348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.07.044
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