HIV-1 integrase binds the viral RNA genome and is essential during virion morphogenesis

While an essential role of HIV-1 integrase (IN) for integration of viral cDNA into human chromosome is established, studies with IN mutants and allosteric IN inhibitors (ALLINIs) have suggested that IN can also influence viral particle maturation. However, it has remained enigmatic as to how IN cont...

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Bibliografske podrobnosti
izdano v:Cell
Main Authors: Kessl, Jacques J., Kutluay, Sebla B., Townsend, Dana, Rebensburg, Stephanie, Slaughter, Alison, Larue, Ross C., Shkriabai, Nikoloz, Bakouche, Nordine, Fuchs, James R., Bieniasz, Paul D., Kvaratskhelia, Mamuka
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003418/
https://ncbi.nlm.nih.gov/pubmed/27565348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.07.044
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