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Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization

The main cause of death globally remains debilitating heart conditions, such as dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM), which are often due to mutations of specific components of adhesion complexes. Vinculin regulates these complexes and plays essential roles in intercala...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Chinthalapudi, Krishna, Rangarajan, Erumbi S., Brown, David T., Izard, Tina
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003255/
https://ncbi.nlm.nih.gov/pubmed/27503891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600702113
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