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The interaction of talin with the cell membrane is essential for integrin activation and focal adhesion formation

Multicellular organisms have well-defined, tightly regulated mechanisms for cell adhesion. Heterodimeric αβ integrin receptors play central roles in this function and regulate processes for normal cell functions, including signaling, cell migration, and development, binding to the extracellular matr...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Chinthalapudi, Krishna, Rangarajan, Erumbi S., Izard, Tina
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187153/
https://ncbi.nlm.nih.gov/pubmed/30254158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806275115
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