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Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization

The main cause of death globally remains debilitating heart conditions, such as dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM), which are often due to mutations of specific components of adhesion complexes. Vinculin regulates these complexes and plays essential roles in intercala...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Chinthalapudi, Krishna, Rangarajan, Erumbi S., Brown, David T., Izard, Tina
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003255/
https://ncbi.nlm.nih.gov/pubmed/27503891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600702113
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