Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin

The cytoskeletal protein talin activates integrin receptors by binding of its FERM domain to the cytoplasmic tail of β-integrin. Talin also couples integrins to the actin cytoskeleton, largely by binding to and activating the cytoskeletal protein vinculin, which binds to F-actin through the agency o...

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Bibliografiske detaljer
Main Authors: Yogesha, S D, Rangarajan, Erumbi S, Vonrhein, Clemens, Bricogne, Gerard, Izard, Tina
Format: Artigo
Sprog:Inglês
Udgivet: Wiley Subscription Services, Inc., A Wiley Company 2012
Fag:
Protein Structure Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375758/
https://ncbi.nlm.nih.gov/pubmed/22334306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2041
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