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Intermolecular versus intramolecular interactions of the vinculin binding site 33 of talin

The cytoskeletal proteins talin and vinculin are localized at cell-matrix junctions and are key regulators of cell signaling, adhesion, and migration. Talin couples integrins via its FERM domain to F-actin and is an important regulator of integrin activation and clustering. The 220 kDa talin rod dom...

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Bibliographic Details
Main Authors: Yogesha, SD, Sharff, A, Bricogne, G, Izard, T
Format: Artigo
Language:Inglês
Published: Wiley Subscription Services, Inc., A Wiley Company 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189532/
https://ncbi.nlm.nih.gov/pubmed/21648001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.671
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