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Novel Vinculin Binding Site of the IpaA Invasin of Shigella

Internalization of Shigella into host epithelial cells, where the bacteria replicates and spreads to neighboring cells, requires a type 3 secretion system (T3SS) effector coined IpaA. IpaA binds directly to and activates the cytoskeletal protein vinculin after injection in the host cell cytosol, and...

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Auteurs principaux: Park, HaJeung, Valencia-Gallardo, Cesar, Sharff, Andrew, Van Nhieu, Guy Tran, Izard, Tina
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123088/
https://ncbi.nlm.nih.gov/pubmed/21525010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.184283
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