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Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri

Invasion of epithelial cells by Shigella flexneri is characterized by cytoskeletal rearrangements of the host cell membrane, promoting internalization of the bacterium. The bacterial effector IpaA is injected into the epithelial cell by a type III secretion apparatus and recruits vinculin to regulat...

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Hlavní autoři: Hamiaux, Cyril, van Eerde, André, Parsot, Claude, Broos, Jaap, Dijkstra, Bauke W
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1525141/
https://ncbi.nlm.nih.gov/pubmed/16826238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400753
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