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CRISPR: a Versatile Tool for Both Forward and Reverse Genetics Research

Human genetics research employs the two opposing approaches of forward and reverse genetics. While forward genetics identifies and links a mutation to an observed disease etiology, reverse genetics induces mutations in model organisms to study their role in disease. In most cases, causality for muta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Genet
Hauptverfasser: Gurumurthy, Channabasavaiah B., Grati, M'hamed, Ohtsuka, Masato, Schilit, Samantha L.P., Quadros, Rolen M., Liu, Xue Zhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002245/
https://ncbi.nlm.nih.gov/pubmed/27384229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-016-1704-4
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