Dysregulation of the (immuno)proteasome pathway in malformations of cortical development

BACKGROUND: The proteasome is a multisubunit enzyme complex involved in protein degradation, which is essential for many cellular processes. During inflammation, the constitutive subunits are replaced by their inducible counterparts, resulting in the formation of the immunoproteasome. METHODS: We in...

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Détails bibliographiques
Publié dans:J Neuroinflammation
Auteurs principaux: van Scheppingen, J., Broekaart, D. W. M., Scholl, T., Zuidberg, M. R. J., Anink, J. J., Spliet, W. G., van Rijen, P. C., Czech, T., Hainfellner, J. A., Feucht, M., Mühlebner, A., van Vliet, E. A., Aronica, E.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002182/
https://ncbi.nlm.nih.gov/pubmed/27566410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0662-z
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