Dysregulation of the (immuno)proteasome pathway in malformations of cortical development

BACKGROUND: The proteasome is a multisubunit enzyme complex involved in protein degradation, which is essential for many cellular processes. During inflammation, the constitutive subunits are replaced by their inducible counterparts, resulting in the formation of the immunoproteasome. METHODS: We in...

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Pubblicato in:J Neuroinflammation
Autori principali: van Scheppingen, J., Broekaart, D. W. M., Scholl, T., Zuidberg, M. R. J., Anink, J. J., Spliet, W. G., van Rijen, P. C., Czech, T., Hainfellner, J. A., Feucht, M., Mühlebner, A., van Vliet, E. A., Aronica, E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002182/
https://ncbi.nlm.nih.gov/pubmed/27566410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0662-z
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