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New insights into a spectrum of developmental malformations related to mTOR dysregulations: challenges and perspectives

In recent years the role of the mammalian target of rapamycin (mTOR) pathway has emerged as crucial for normal cortical development. Therefore, it is not surprising that aberrant activation of mTOR is associated with developmental malformations and epileptogenesis. A broad spectrum of malformations...

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Detalhes bibliográficos
Publicado no:J Anat
Main Authors: Mühlebner, A., Bongaarts, A., Sarnat, H. B., Scholl, T., Aronica, E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704243/
https://ncbi.nlm.nih.gov/pubmed/30901081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joa.12956
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