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New insights into a spectrum of developmental malformations related to mTOR dysregulations: challenges and perspectives

In recent years the role of the mammalian target of rapamycin (mTOR) pathway has emerged as crucial for normal cortical development. Therefore, it is not surprising that aberrant activation of mTOR is associated with developmental malformations and epileptogenesis. A broad spectrum of malformations...

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Detalles Bibliográficos
Publicado en:J Anat
Main Authors: Mühlebner, A., Bongaarts, A., Sarnat, H. B., Scholl, T., Aronica, E.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704243/
https://ncbi.nlm.nih.gov/pubmed/30901081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joa.12956
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