Increased matrix metalloproteinases expression in tuberous sclerosis complex: modulation by microRNA 146a and 147b in vitro

AIM: Matrix metalloproteinases (MMPs) and their endogenous tissue inhibitors (TIMPs) control proteolysis within the extracellular matrix (ECM) of the brain. Dysfunction of this enzymatic system due to brain inflammation can disrupt the blood‐brain barrier (BBB) and has been implicated in the pathoge...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neuropathol Appl Neurobiol
Päätekijät: Broekaart, D. W. M., van Scheppingen, J., Anink, J. J., Wierts, L., van het Hof, B., Jansen, F. E., Spliet, W. G., van Rijen, P. C., Kamphuis, W. W., de Vries, H. E., Aronica, E., van Vliet, E. A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217197/
https://ncbi.nlm.nih.gov/pubmed/31183875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12572
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