Increased expression of matrix metalloproteinase 3 can be attenuated by inhibition of microRNA-155 in cultured human astrocytes

BACKGROUND: Temporal lobe epilepsy (TLE) is a chronic neurological disease, in which about 30% of patients cannot be treated adequately with anti-epileptic drugs. Brain inflammation and remodeling of the extracellular matrix (ECM) seem to play a major role in TLE. Matrix metalloproteinases (MMPs) ar...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Korotkov, Anatoly, Broekaart, Diede W. M., van Scheppingen, Jackelien, Anink, Jasper J., Baayen, Johannes C., Idema, Sander, Gorter, Jan A., Aronica, Eleonora, van Vliet, Erwin A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054845/
https://ncbi.nlm.nih.gov/pubmed/30031401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1245-y
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