Triptolide Abrogates Growth of Colon Cancer and Induces Cell Cycle Arrest by Inhibiting Transcriptional Activation of E2F

BACKGROUND: Despite significant progress in diagnostics and therapeutics, over fifty thousand patients die from colorectal cancer annually. Hence there is urgent need for new lines of treatment. Triptolide, a natural compound isolated from the Chinese herb Tripterygium wilfordii, is effective agains...

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Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Oliveira, Amanda, Beyer, Georg, Chugh, Rohit, Skube, Steven J, Majumder, Kaustav, Banerjee, Sulagna, Sangwan, Veena, Li, Lihua, Dawra, Rajinder, Subramanian, Subbaya, Saluja, Ashok, Dudeja, Vikas
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001951/
https://ncbi.nlm.nih.gov/pubmed/25893635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2015.46
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