Single-cell transcript profiles reveal multilineage priming in early progenitors derived from Lgr5(+) intestinal stem cells

Lgr5(+) intestinal stem cells (ISC) drive epithelial self-renewal, and their immediate progeny – intestinal bipotential progenitors – produce absorptive and secretory lineages via lateral inhibition. To define features of early transit from the ISC compartment, we used a microfluidics approach to me...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Cell Rep
Главные авторы: Kim, Tae-Hee, Saadatpour, Assieh, Guo, Guoji, Saxena, Madhurima, Cavazza, Alessia, Desai, Niyati, Jadhav, Unmesh, Jiang, Lan, Rivera, Miguel N., Orkin, Stuart H., Yuan, Guo-Cheng, Shivdasani, Ramesh A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001892/
https://ncbi.nlm.nih.gov/pubmed/27524622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.056
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы