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Characterizing heterogeneity in leukemic cells using single-cell gene expression analysis

BACKGROUND: A fundamental challenge for cancer therapy is that each tumor contains a highly heterogeneous cell population whose structure and mechanistic underpinnings remain incompletely understood. Recent advances in single-cell gene expression profiling have created new possibilities to character...

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Publicat a:Genome Biol
Autors principals: Saadatpour, Assieh, Guo, Guoji, Orkin, Stuart H, Yuan, Guo-Cheng
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262970/
https://ncbi.nlm.nih.gov/pubmed/25517911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0525-9
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