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Bifurcation analysis of single-cell gene expression data reveals epigenetic landscape

We present single-cell clustering using bifurcation analysis (SCUBA), a novel computational method for extracting lineage relationships from single-cell gene expression data and modeling the dynamic changes associated with cell differentiation. SCUBA draws techniques from nonlinear dynamics and stoc...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Marco, Eugenio, Karp, Robert L., Guo, Guoji, Robson, Paul, Hart, Adam H., Trippa, Lorenzo, Yuan, Guo-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284553/
https://ncbi.nlm.nih.gov/pubmed/25512504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408993111
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