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Mesoscale modeling reveals formation of an epigenetically driven HOXC gene hub
Gene expression is orchestrated at the structural level by nucleosome positioning, histone tail acetylation, and linker histone (LH) binding. Here, we integrate available data on nucleosome positioning, nucleosome-free regions (NFRs), acetylation islands, and LH binding sites to “fold” in silico the...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6421463/ https://ncbi.nlm.nih.gov/pubmed/30718394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816424116 |
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