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Mesoscale Modeling Reveals Hierarchical Looping of Chromatin Fibers Near Gene Regulatory Elements

While it is well recognized that chromatin loops play an important role in gene regulation, structural details regarding higher order chromatin loops are only emerging. Here we present a systematic study of restrained chromatin loops ranging from 25–427 nucleosomes (fibers of 5–80 Kb DNA in length),...

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Vydáno v:J Phys Chem B
Hlavní autoři: Bascom, Gavin D, Sanbonmatsu, Karissa Y, Schlick, Tamar
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6268121/
https://ncbi.nlm.nih.gov/pubmed/27218881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b03197
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