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Mesoscale Modeling Reveals Hierarchical Looping of Chromatin Fibers Near Gene Regulatory Elements
While it is well recognized that chromatin loops play an important role in gene regulation, structural details regarding higher order chromatin loops are only emerging. Here we present a systematic study of restrained chromatin loops ranging from 25–427 nucleosomes (fibers of 5–80 Kb DNA in length),...
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| Gepubliceerd in: | J Phys Chem B |
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| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6268121/ https://ncbi.nlm.nih.gov/pubmed/27218881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b03197 |
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