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The use of an artificial nucleotide for polymerase-based recognition of carcinogenic O(6)-alkylguanine DNA adducts
Enzymatic approaches for locating alkylation adducts at single-base resolution in DNA could enable new technologies for understanding carcinogenesis and supporting personalized chemotherapy. Artificial nucleotides that specifically pair with alkylated bases offer a possible strategy for recognition...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5001614/ https://ncbi.nlm.nih.gov/pubmed/27378785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw589 |
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