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The use of an artificial nucleotide for polymerase-based recognition of carcinogenic O(6)-alkylguanine DNA adducts

Enzymatic approaches for locating alkylation adducts at single-base resolution in DNA could enable new technologies for understanding carcinogenesis and supporting personalized chemotherapy. Artificial nucleotides that specifically pair with alkylated bases offer a possible strategy for recognition...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wyss, Laura A., Nilforoushan, Arman, Williams, David M., Marx, Andreas, Sturla, Shana J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001614/
https://ncbi.nlm.nih.gov/pubmed/27378785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw589
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