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Sequence-Specific Quantitation of Mutagenic DNA Damage via Polymerase Amplification with an Artificial Nucleotide
[Image: see text] DNA mutations can result from replication errors due to different forms of DNA damage, including low-abundance DNA adducts induced by reactions with electrophiles. The lack of strategies to measure DNA adducts within genomic loci, however, limits our understanding of chemical mutag...
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| Veröffentlicht in: | J Am Chem Soc |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical
Society
2020
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7192524/ https://ncbi.nlm.nih.gov/pubmed/32196326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b11746 |
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