Sequence-Specific Quantitation of Mutagenic DNA Damage via Polymerase Amplification with an Artificial Nucleotide

[Image: see text] DNA mutations can result from replication errors due to different forms of DNA damage, including low-abundance DNA adducts induced by reactions with electrophiles. The lack of strategies to measure DNA adducts within genomic loci, however, limits our understanding of chemical mutag...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Aloisi, Claudia M. N., Nilforoushan, Arman, Ziegler, Nathalie, Sturla, Shana J.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192524/
https://ncbi.nlm.nih.gov/pubmed/32196326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b11746
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