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Direct and site-specific quantification of RNA 2′-O-methylation by PCR with an engineered DNA polymerase

Methylation of the 2′-hydroxyl-group of ribonucleotides is found in all major classes of RNA in eukaryotes and is one of the most abundant posttranscriptional modifications of stable RNAs. In spite of intense studies, the multiple functions of RNA 2′-O-methylation are still not understood. One major...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Aschenbrenner, Joos, Marx, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856998/
https://ncbi.nlm.nih.gov/pubmed/27016740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw200
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