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Activation of aminoimidazole carcinogens by nitrosation: mutagenicity and nucleotide adducts
2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) are heterocyclic amines (HCA) derived from high temperature cooking of meat and thought to cause colon cancer in humans. Reactive nitrogen oxygen species, which are mediators of the inflammatory re...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2775548/ https://ncbi.nlm.nih.gov/pubmed/19449459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2008.12.007 |
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